Tribology of enzymatically degraded cartilage mimicking early osteoarthritis
Abstract Healthy cartilage is a water-filled super lubricious tissue.Collagen type II provides it structural stability, and proteoglycans absorb water to keep the cartilage in a swollen condition, providing it the ability to creep and provide weeping lubrication.Osteoarthritis (OA) is a degenerative and equi-jec 7 debilitating disorder of diarthrod